The UK facility, tasked with building the Vivaro van, employs over 1,500 people in the Luton area and has been producing the Vivaro van since 2001.
The Vauxhall Vivaro, recently voted in the top ten most reliable vans in the UK by the top 50 contract hire and leasing companies, was designed as a joint venture between Renault and Vauxhall.
A Renault-badged version, the Renault Trafic, was also introduced at the same time and is built alongside the Vivaro at the Luton plant.
The Luton plant produces 60,000 vehicles every year, while Vauxhall Astravan production at the Ellesmere Port plant in Cheshire adds to the number, making Vauxhall the biggest commercial vehicle manufacturer in the UK.
The Vivaro van is a medium panel van designed to compete with the market leader, the Ford Transit. Vauxhall Vivaro prices start from £17,691 and it comes in standard, Sportive, Doublecab, Dropside, 9-seat Combi and 12-seat Minibus body styles.
Engines range from a 2.0-litre CDTi in 90 or 155PS and a 2.5-litre CDTi unit. Both the 155PS 2.0-litre and 2.5-litre engines are available with a choice of six-speed manual or a Tecshift automatic gearbox, while the 90PS engine comes with manual transmission only.
Speaking about the 750,000th Vauxhall Vivaro, Mark Stein, Plant Director, said: "Over the last nine years, the success of the multi-award winning Vivaro has been down to the exceptional quality that our hard working and dedicated workforce builds into every example.
"This milestone is a mark of the continued strength of Vivaro in markets across Europe. We are very proud to build it here in the UK."